{"id":337,"date":"2023-05-16T16:42:43","date_gmt":"2023-05-16T16:42:43","guid":{"rendered":"https:\/\/noahsnestedu.com\/blog\/?p=337"},"modified":"2023-05-16T16:42:43","modified_gmt":"2023-05-16T16:42:43","slug":"oet-reading-battens-disease","status":"publish","type":"post","link":"https:\/\/noahsnestedu.com\/blog\/oet-reading-battens-disease\/","title":{"rendered":"OET READING &#8211; BATTENS DISEASE"},"content":{"rendered":"\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/noahsnestedu.com\/blog\/wp-content\/uploads\/OET-RDG.-PASSAGE-MAY-3-WEEK.pdf\" type=\"application\/pdf\" style=\"width:100%;height:848px\" aria-label=\"Embed of OET-RDG.-PASSAGE-MAY-3-WEEK.\"><\/object><a id=\"wp-block-file--media-1018603e-468b-4524-ada3-5e995b9564c3\" href=\"https:\/\/noahsnestedu.com\/blog\/wp-content\/uploads\/OET-RDG.-PASSAGE-MAY-3-WEEK.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">OET-RDG.-PASSAGE-MAY-3-WEEK<\/a><a href=\"https:\/\/noahsnestedu.com\/blog\/wp-content\/uploads\/OET-RDG.-PASSAGE-MAY-3-WEEK.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-1018603e-468b-4524-ada3-5e995b9564c3\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Battens Disease<\/p>\n<p>The Neuronal Ceroid Lipofuscinoses (NCL&#8217;s), also known as Battens disease, are a collection of congenital neurodegenerative conditions that span from prenatal life to late adulthood with an incidence of 1:12,500. They comprise of at least 8<br \/>\nautosomal recessive disorders defined by having a mutation in a CLN gene, either coding for an enzyme (CLN1 and CLN2) or a transmembrane protein (CLN3,<br \/>\nCLN5, CLN6 and CLN8) with all disorders having common clinical features, including progressive visual loss to blindness, seizures, speech disturbances, motor degeneration and intellectual decline, leading to early death LINCL has an incidence of 0.36-0.46 per 100,000 with an age of onset of between 2-4 years, and<br \/>\ndeath commonly anticipated in the early teenage years. LINCL is caused by a mutation of the CLN2 gene on chromosome 11p15, of which 98 mutations are known, three of which account for the majority of cases.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":true,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-337","post","type-post","status-publish","format-standard","hentry","category-oet"],"_links":{"self":[{"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/posts\/337","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/comments?post=337"}],"version-history":[{"count":2,"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/posts\/337\/revisions"}],"predecessor-version":[{"id":340,"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/posts\/337\/revisions\/340"}],"wp:attachment":[{"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/media?parent=337"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/categories?post=337"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/noahsnestedu.com\/blog\/wp-json\/wp\/v2\/tags?post=337"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}